Our Publications

As a science-driven company, we proudly publish numerous scientific papers every year in high-impact journals. Please feel free to contact our Science-team if you have questions or comments to our publications, or proposals for new scientific collaborations: science@nbcd.com

2 publications found

May 07, 2021

Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study

The FORWARD (FGF-18 Osteoarthritis Randomized Trial with Administration of Repeated Doses) trial assessed efficacy and safety of the potential disease-modifying osteoarthritis drug (DMOAD) sprifermin in patients with knee osteoarthritis. Here, we report 5-year efficacy and safety results.

Journals:

Annals of the Rheumatic Diseases

Authors:

Eckstein F , Hochberg MC , Guehring H , Moreau F , Ona V , Bihlet AR , Byrjalsen I , Andersen JR , Daelken B , Guenther O , Ladel C , Michaelis M , Conaghan PG

Osteoarthritis

March 11, 2021

The effects of sprifermin on symptoms and structure in a subgroup at risk of progression in the FORWARD knee osteoarthritis trial

To assess pain outcomes and cartilage thickness change in a subgroup at risk (SAR) of further progression in the FORWARD trial of knee osteoarthritis patients treated with sprifermin.

Journals:

Seminars in Arthritis and Rheumatism

Authors:

Guehring H , Moreau F , Daelken B , Ladel C , Guenther O , Bihlet AR , Wirth W , Eckstein F , Hochberg MC , Conaghan PG

Osteoarthritis